PostDoc in Molecular and Functional Neurobiology Group
Université du Luxembourg
Belval, Esch-sur-Alzette, LU
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The University About us...

The University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character.

The University was founded in 2003 and counts more than 6,700 students and more than 2,000 employees from around the world.

The University’s faculties and interdisciplinary centres focus on research in the areas of Computer Science and ICT Security, Materials Science, European and International Law, Finance and Financial Innovation, Education, Contemporary and Digital History.

In addition, the University focuses on cross-disciplinary research in the areas of Data Modelling and Simulation as well as Health and System Biomedicine.

Times Higher Education ranks the University of Luxembourg #3 worldwide for its international outlook, #20 in the Young University Ranking 2021 and among the top 250 universities worldwide.

Within the University, the Luxembourg Centre for Systems Biomedicine (LCSB) is a highly interdisciplinary research centre (IC), integrating experimental biology and computational biology approaches in order to develop the foundation of a future predictive, preventive and personalized medicine.

Your Role...

The postdoctoral fellow will be involved in the RareCom project entitled : From rare to common disease : Use of ATP13A2-deficient iPSC-based models for drug discovery in Parkinson’s disease .

The aim of this FNR-funded project is to investigate the role of the lysosomal protein ATP13A2 in the context of neurodegeneration.

Patient-derived cellular models will be used to uncover disease mechanisms and to uncover novel therapeutic candidates.

Your tasks / mission :

  • Generation / maintenance of induced pluripotent stem cells and subsequent differentiation into dopaminergic neurons
  • Design and application of experiments to assess the impact of mutations in ATP13A2 on lysosomal, mitochondrial and neuronal function
  • Student supervision
  • What we expect from you

  • PhD in Cellular Biology, Neuroscience, or related discipline
  • Strong interest in interdisciplinary research and cellular models of neurodegeneration
  • Track record in research and laboratory work as documented by publications in internationally acknowledged journals
  • Profound knowledge of molecular genetics, biochemistry and cell biology
  • Expertise with induced pluripotent stem cell models (particularly neurons)
  • Previous experience with high-throughput imaging and automated image analysis is desirable
  • Excellent communication, team-working and interpersonal skills
  • Previous experience as supervisor of students
  • Enthusiasm and great commitment to research
  • Very good command of the English language
  • In Short...

  • Contract Type : Contrat à durée déterminée 24 Mois
  • Work Hours : Full Time 40.0 Heures par Semaine
  • Location : Belval
  • Internal Title : Postdoctoral researcher
  • Job Reference : UOL05263
  • The yearly gross salary for every Postdoctoral Researcher at the UL is EUR 77167 full time

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