Postdoctoral Researcher in Molecular and Functional Neurobiology Group
University of Luxembourg
Luxembourg, Luxembourg
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source : Euraxess
  • About the University*
  • The *University of Luxembourg* aspires to be one of Europe’s most highly regarded universities with a distinctly international and *interdisciplinary character*.

    It fosters the cross-fertilisation of research and teaching, is relevant to its country, is known worldwide for its *research* and *teaching* in targeted areas, and is establishing itself as an innovative model for contemporary European Higher Education.

    It s core asset is its well-connected world-class academic staff which will attract the most motivated, talented and creative students and young researchers who will learn to enjoy taking up challenges and develop into visionary thinkers able to shape society.

    Within the University, the *Luxembourg Centre for Systems Biomedicine (LCSB)* is a highly interdisciplinary *research centre* (IC), integrating experimental biology and computational biology approaches in order to develop the foundation of a future predictive, preventive and personalized medicine.

  • Your Role*
  • The postdoctoral fellow will be involved in the ATTRACT project entitled : *Modelling idiopathic Parkinson’s disease-associated somatic variation in dopaminergic neurons *.

    The aim of this FNR-funded research we aim to investigate the involvement of the mitochondrial genome in the pathogenesis of Parkinson's disease using stem cell-derived cellular models and postmortem brain tissue.

  • Your tasks / mission : *
  • Generation / maintenance of induced pluripotent stem cells and subsequent differentiation into dopaminergic neurons and astrocytes
  • Design and application of experiments to assess the impact of mtDNA maintenance defects on mitochondrial, neuronal and astrocyte function
  • Evaluation of the immune reactivity of mature astrocytes
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