Doctoral researcher (PhD student) in Parkinson's Disease Genetics and Genomics
Université du Luxembourg
Luxembourg, Luxembourg
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Your Role

The Luxembourg Centre for Systems Biomedicine (LCSB) is an interdisciplinary research centre at the University of Luxembourg.

LCSB develops and applies systems-level approaches to gain insight into the molecular and cellular mechanisms of human diseases.

Experimental and computational approaches are combined to analyse the complexity of biological systems underlying disease pathogenesis.

The LCSB is pioneering the way for a predictive, preventive and personalised medicine. Neurodegenerative diseases, especially Parkinson’s disease (PD) are major targets within LCSB’s research activities.

We seek a highly skilled doctoral student to work on an international and interdisciplinary biomedical research project on the identification of genetic risk factors for PD (PD) within the recently founded National Center for Excellence in Research on PD (NCER-

PD, ) and the doctoral training unit PARK-QC - Molecular, Organellar and Cellular Quality Control in Parkinson's disease ().

The project will include genetic and bioinformatics analysis of genotype -and next-generation sequencing data, genetic analysis, and the application of systems biology approaches in the context of the newly established LuxPARK PD cohort.

You will analyze genetic data from a large datasets of PD patients and controls and integrate by integration with available omics databases and by pathway analysis to establish new PD genetic risk factors.

Your Profile

  • Master’s degree (or equivalent) in Computational Biology, Bioinformatics, Human Genetics, Systems Biology or related disciplines.
  • Basic understanding of NGS genomics technologies and state-of-the-art bioinformatics software tools.
  • Good knowledge of human genetics, molecular biology, systems biology, computational modeling, or simulation.
  • Knowledge of at least one programming language (Python, Perl, C++, Java, etc).
  • Basic Linux / Unix skills.
  • Strong interest in interdisciplinary research and systems biology
  • Excellent working knowledge in English (additional language skills, particularly French or German, will be advantageous)
  • Excellent communication skills
  • We offer

  • Fully funded position (within the doctoral training unit PARK-QC).
  • A scientifically stimulating, innovative, dynamic, well-equipped, and international working environment.
  • Opportunity to participate in the development of the recently created LCSB and to work with our world-wide academic partners.
  • Enrolment in the Doctoral School of the University of Luxembourg to complement the research-oriented PhD program by courses in experimental biology, bioinformatics or other research-related skills ().
  • In-depth training in cutting edge technologies used in systems biology.
  • Travel opportunities for training and meeting with our collaborators.
  • Numerous training opportunities in (molecular) biology, systems biology, and bioinformatics

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