Post-Doctoral Fellow: Gut microbiome and mucosal barrier in multiple sclerosis
Luxembourg Institute of Health (LIH)
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source : Euraxess

Luxembourg Institute of Health (LIH) is the leading public research center in Luxembourg for basic, pre-clinical and clinical research in biomedicine and public health.

Our clinically-oriented biomedical research activities in Oncology, Infection & Immunity and Population Health encompass the generation of knowledge on the pathogenesis, diagnosis and treatment of diseases with large impacts on public health and the epidemiological surveillance of these diseases.

With the mission to deliver scientific, economic and societal value for Luxembourg, LIH aims to translate knowledge into clinical applications impacting on healthcare systems while shaping personalized medicine.

The Eco-Immunology and Microbiome Unit within the Department of Infection and Immunity is seeking a : *Post-Doctoral Fellow : Gut microbiome and mucosal barrier in multiple sclerosis*

2 to 3 year fixed-term contract (possibility of extension), full time

We are looking for a talented candidate to apply for a Marie Skłodowska-Curie Actions (MSCA) Individual postdoctoral fellowship 2020.

The interested candidate will submit an MSCA fellowship jointly with the Ecoimmunology & Microbiome Group’ headed by Prof.

Mahesh S. Desai. The research project will focus on the interactions between diet, the gut microbiome and colonic mucus in a neurodegenerative disease multiple sclerosis (MS).

The project is based on the published work (Desai et al., Cell, 2016; Martens Desai, Nature Reviews Microbiology, 2018) on the same topic and involves gnotobiotic mouse models, synthetic microbial communities, MS patient cohorts and key international collaborations in Europe, USA and Japan.

The postdoc will participate in an exciting research program in an international research team with prior success with the MSCA applications.

Scientific and professional guidance will be provided to submit the application for a postdoctoral fellowship that, if successful, could be initiated between spring 2021 to early 2022.

A 'bridge funding’ option may be available to start earlier in 2020 before the outcome of the fellowship application.

  • Key Accountabilities*
  • Submit an MSCA individual fellowship together with the host institute on an exciting research topic about
  • understanding the microbiome-based mechanisms of MS pathogenesis.

  • Carry out a research project independently (drafting, validation, etc.) and set up follow up projects.
  • Participate in the execution of a research project (implementation, follow-up, planning) within a research team
  • while trying to optimize productivity.

  • Design and execute experiments as required by the project.
  • Write scientific articles for peer-reviewed international journals.
  • Develop scientific methodology and techniques adapted to the research project.
  • Evaluate research results for patent filing.
  • Present the work as well as results during research unit meetings and at international meetings, congresses.
  • Establish and disseminate the bibliography to the other researchers, students and technicians.
  • Communicate problems and suggestions for possible solutions in a clear way.
  • Participate in the societal dimension : dissemination of simplified research results to the general public (through articles, conferences, etc.).
  • Key Skills, Experience and Qualifications*
  • PhD degree in Microbiology / Immunology / Neurobiology / Biochemistry / Molecular Biology / Bioinformatics
  • High level of motivation for research, attention to detail, scientific creativity and originality, and writing skills
  • Languages skills : fluent command of English
  • For more information please contact : * Prof. Mahesh Desai :
  • Website : * Eco-Immunology and Microbiome Unit on
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