Internship position (Master2 student) in Biomonitoring
Luxembourg Institute of Health
Strassen, Luxembourg
il y a 5j

NoSTra-ED - Novel Strategies for assessingexposure to short-lived endocrine disruptors.

Biological fluids (blood andurine), which are considered the matrices of choice for the assessment of humanexposure to pollutants, are of limited use for short-

life endocrine disruptors(e.g. bisphenol A, phthalates ). The main limit is related to the strongshort-term variability of the concentration of these molecules in thesematrices.

On the contrary, hair analysis provides information that integratesexposure over longer period and therefore represents a particularly interestingalternative.

The objective of the NoStra-ED project is to determine thevariability of the urinary concentration of short-life endocrine disruptors andto compare the information obtained from two matrices (urine and hair) for thebiomonitoring of human exposure to these pollutants within a follow-

up on humanvolunteers and animal experimentation. As part of this Master II internship,the candidate will be trained in various state-

of-the-art analytical techniquessuch as liquid and gas chromatography coupled with tandem mass spectrometricdetection (LC-

MS / MS and GC-MS / MS) as well as pre-analytical work(extraction from biological matrices, purification and concentration ofextracts) with the support of highly skilled engineers.

The candidate may alsoparticipate in the analysis and processing of the data produced : resultsformatting and interpretation, and statistical analysis under the supervisionof a statistician specialized in the field of biomonitoring

What we offer and conditions

  • Students will have the opportunity towork in an interactive and international scientific environment, attendconferences by eminent scientists from abroad, and present their own workduring lab meetings.
  • They will receive training in highlevel analytical technique (LC-MS / MS and GC-MS / MS) and analytical softwares,data interpretation and statistical analysis.
  • Applicants must be affiliated totheir own University. English and / or French is mandatory.
  • Master students will receive 500€ / month unless they have their own funding source, e.g. Erasmus grant
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